Right now hotkeys don’t support different keyboard layouts, which is quite inconvenient. I’m sure there are complete mapping tables that show which keys correspond to important hotkeys like: T, R, U, I, A and others in various layouts. I think it should be possible to map them to the English layout without any issues.

P.S. Just eight years ago there was a request on GitHub to add hotkeys — it’s surprising that they didn’t exist here at all before that. (ProtonMail/WebClients/issues/65)